University of Hawaii

MMS Faculty

Randall F. Holcombe, MD, MBA

Randall F. Holcombe, MD, MBA is Director of the University of Hawai‘i Cancer Center, assuming this post in October, 2016. He previously served as Chief Medical Officer-Cancer for the Mount Sinai Health System in New York and Deputy Director of the Tisch Cancer Institute at the Icahn School of Medicine at Mount Sinai. He received his MD from NJ Medical School and an MBA from the Zicklin School of Business at Baruch College. His post-doctoral clinical and research training was completed at Brigham & Women’s Hospital and Harvard Medical School in Boston.

Dr. Holcombe has had extensive experience over the past 25 years in translational research and the conduct of oncology clinical trials. His research activities have focused on clinical research for patients with colorectal cancer, laboratory studies involving signaling pathways in the colon tumor microenvironment and the role of natural products in modulating cancer biology. Most recently, his research focus has been on health care delivery science as a means to define new approaches for the delivery of quality cancer care. His research has been funded by the NIH and multiple foundations and has resulted in more than 100 peer-reviewed manuscript publications. Dr. Holcombe is Chair of the Physicians’ Clinical Leadership Initiative for the Association of American Cancer Institutes and serves on the editorial board for the Journal of Oncology Practice.

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