UH Med Now - Research

Pictured: Axel Lehrer in the lab. Deborah Manog Dimaya photo. By Deborah Manog Dimaya, Interim Director of Communications A University of Hawaiʻi (UH) at Mānoa researcher, in collaboration with a pharmaceutical company, has developed a vaccine candidate that shows promise in rapidly inducing immunity to the novel coronavirus in pre-clinical trials. Axel Lehrer, an assistant […]

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COVID-19 dysregulates a hormone system causing damage to the heart and lungs; a common blood pressure drug just might help. HONOLULU— The first outpatient clinical trial in Hawaii is aimed at finding an effective treatment for patients with COVID-19 using telmisartan, a medication commonly used for blood pressure control. Researchers at the John A. Burns […]

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White Coat Ceremony for the University of Hawaii – Mānoa JABSOM class of 2020 brand new Internal Medicine residents at The Queen’s Medical Center. The first graduating class of COVID-19 in their masks. MASK UP!    This most recent Communication Protocol applies to all JABSOM employees and learners, including those working on the UH Manoa […]

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Robert Mann, PhD, DABFA, FCPP, Adjunct Professor in Anatomy and Pathology, talks to his audience while Kiana Miller readies the bones and monitors the chats. Kiana plans to seek a graduate degree in Physical Anthropology beginning in the fall of 2020. Robert Mann, PhD, DABFA, FCPP, and Adjunct Professor in Anatomy and Pathology, presented a […]

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Date: July 15th, 2020 in Comment-Post, External News, Research

The relation between selenium, GPX1, ebselen, and SARS-CoV-2 Mpro (Nsp5). Selenium (Se) availability regulates expression of GPX1, which, in turn, mitigates oxidative stress. If left unchecked, oxidative stress promotes viral mutagenesis. The selenium-containing compound ebselen mimics GPX activity and is a potent inhibitor of Mpro (Nsp5). GPX1 also interacts with Mpro in a yet-to-be-characterized fashion. Mpro is essential for […]

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Date: July 1st, 2020 in Community Outreach, Faculty, JABSOM News, Research

ARTICLE LINK:  Covid-19 Antibody Testing – Is There Value Beyond the Result?  Drs. Melinda Ashton and Shilpa Patel are long-time faculty members in the JABSOM Department of Pediatrics, who with two medical students surveyed Hawaii Pacific Health (HPH) employees who volunteered for the company’s offer of free COVID-19 antibody testing. Despite a low prevalence of […]

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