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VIDEO: $5.3M funding for world-famous reproductive science lab, Institute for Biogenesis Research at UH JABSOM

Date: September 15th, 2019 in JABSOM News    Print or PDF

Four of the IBR key staff.

Pictured: Stefan Moisyadi, PhD, Associate Professor; B.H. and Alice C. Beams Endowed Professor in Cancer Research at JABSOM; Michelle Kerklo, Fiscal Administrator; Johann Urschitz, PhD, Assistant Professor; William Ward, PhD, IBR Professor & Director; Chief, Research Division, Lakshmi Devi and Devraj Sharma Endowed Chair, Department of OB-GYN and Women’s Health, UHM JABSOM. Photo by Deborah Manog Dimaya.

Newest 5-year grant will advance work of scientists who produced “glowing green mice,” and earlier laid the scientific groundwork for invitro fertilization

By Tina Shelton, JABSOM Communications Director

The University of Hawaiʻi(UH) Mānoa has received a $5.3 million grant to continue research at the laboratory that became world-famous for producing mice and eventually other animals that glow green under ultraviolet light. This grant will allow the Institute for Biogenesis Research (IBR) to produce transgenic mice for other researchers seeking medical cures at UH.

The "glowing green mice" in the lab at UH M?noa.

The “glowing green mice” in the IBR lab at UH Mānoa in 1999.

The mouse and its pups glowed green because jellyfish genes had been inserted into a mouse embryo to demonstrate the lab’s successful technique for inserting DNA from an unrelated organism into that of another animal. The first green mouse was born, and then she transferred the glowing gene to her pups.
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Our wiki, or quick, video reports on the $5.3M Center of Biomedical Research Excellence grant received by the Institute for Biogenesis Research at the University of Hawaiʻi Mānoa John A. Burns School of Medicine (JABSOM). The IBR is internationally recognized for several techniques developed by its scientists. Dr. William “Steve” Ward is interviewed. This is the third of three COBRE grants received by the IBR. JABSOM Communications Video, 2019. Music is creative commons, copyright free from the YouTube music library, title is “Ticker”.

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This is the third consecutive five-year funding award the IBR has been selected to receive.

Dr. Ward pose.

“We’ll be able to build on our previous 10 years of research,” said Dr. William Ward, Director of the Institute for Biogenesis Research.

“All along, we’ve been developing new technologies to make us even better,” said Dr. Steven Ward, Director of the IBR. “With this grant, we’ll be able to build on our previous 10 years of research to provide genetically altered mice for anybody at UH. These are models that scientists can use for their research — mice with specific diseases or with a certain gene missing or with a gene present so the researchers can see what they can do with it.”

“Making a better mouse models allows scientists to advance cures,” said Dr. William Ward, IBR Director.

Since mice are the closest animals to humans for biological testing, Dr. Ward said, making a better mouse models allows scientists to advance cures.

The IBR building at UH Manoa

The federal funding from the National Institutes of Health (NIH), Institutes of General Medical Sciences (NIGMS) will support collaborations between the IBR, part of the UH Mānoa John A. Burns School of Medicine, and its Reproductive Biology Departments of Anatomy, Biochemistry & Physiology and Obstetrics, Gynecology & Women’s Health.

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